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Enabling greater analytical depth with electron-based fragmentation
Unprecedented speed & simplicity at half the cost.

Our company is committed to providing customers with superior fragmentation at a fraction of market price. Learn how e-MSion is revolutionizing the field of mass spectrometry with our ExD Cell.

What Can e-MSion Do for You?

e-MSion, Inc. aims to advance proteomics research by improving the accessibility of electron-based fragmentation in mass spectrometry.  Our name is an amalgam of electrons, Mass Spectrometry, and ions. We offer a device, the ExD Cell, that enables a type of fragmentation, similar to electron-capture dissociation (ECD), as an add-on to virtually any type of mass spectrometer. This unique type of fragmentation produced by our device enables fast, comprehensive characterization of ions without the experimental complexity of other competing technologies on the market today.

e-MSion is the first to make ECD technically feasible on instruments that are in the low- to mid-price range. As a result, our device makes ECD more accessible “for the masses.” Our universally-compatible ExD Cell device can give life science researchers the ability to more comprehensively characterize their molecules of interest.

  • Easy to use; one set of experimental conditions for multiple analytes
  • Enables characterization of labile post-translational modifications like phosphorylation, glycosylation, and 2H incorporation​
  • Provides complementary fragmentation to CID
  • Installation has minimal effect on the parent instrument’s capabilities
  • Efficiency increases with ion charge, making top-down protein analysis practical
  • Enables aspartate/isoaspartate and leucine/isoleucine identification
VIRTUAL EVENT
November 10-11, 2020 8:00am PST
Solving the Unsolved in Mass Spec; Agilent Innovation and Collaboration For Today's Lab
Speakers: John Fjeldsted, PhD; Kaylie Kirkwood; Peter Rye, PhD; Joseph S. Beckman, PhD; Caroline S. Chu, PhD; Dan Cuthbertson, PhD; Karen Yannell. PhD; Vladimir M. Doroshenko, PhD; Eugene Moskovets, PhD; Richard Lee; Emily Parry, PhD; Paul Auger; Linfeng Wu, PhD; Patrick Cronan; Sheher Banu Mohsin, PhD; Rebecca Glaskin, PhD; Christopher Mallis; Cody Schwarzer; Pete Stone; Harsha Gunawardena, PhD; Dr. Julie Ciccelli; Jim Lau

Featured Publications

Direct Determination of Antibody Chain Pairing by Top-down and Middle-down Mass Spectrometry Using Electron Capture Dissociation and Ultraviolet Photodissociation
Charge Movement and Structural Changes in the Gas-Phase Unfolding of Multimeric Protein Complexes Captured by Native Top-Down Mass Spectrometry
Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility...

To view more publications that feature our ExD Cell in action, please visit our Publications page.

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