Valery Voinov is one of e-MSion’s founders and the principal inventor of its current core technology. For the past almost forty years, he has devoted himself to studying gas-phase interactions between electrons and molecules. As a result of this career-long activity, he has acquired considerable expertise in electron ionization techniques. He started working at The Pacific Institute for Bioorganic Chemistry (PIBOC) in 1979, where he became involved in the instrumental development of a resonance electron capture (REC) mass spectrometer – computer system. Another part of his research at PIBOC concerned the structural investigation of organic substances by REC techniques. After working for two years at the University of Antwerp, where he modified commercially available instruments for operation in the REC mode to study lipids, he moved to Oregon State University in 2002. Working with Doug Barofsky and Joe Beckman for the past years, he has been engaged in the development of a practicable electromagnetostatic electron-capture dissociation (ECD) device. These efforts proved to be exceedingly fruitful – the culmination of which is a new device for performing ECD that can be installed in any type of mass spectrometer.
Jared Shaw Ph.D is passionate about the development of novel instrumentation and methods for top-down proteomics and native mass spectrometry. He graduated from The University of Texas at Austin in 2013 with a Ph.D in Analytical chemistry under supervision from Prof. Jennifer Brodbelt. During his graduate studies, Jared’s efforts were broadly aimed at the development of novel tandem mass spectrometry (MS/MS) methods for proteomics applications. Most notable was his development of 193 nm ultraviolet photodissociation (UVPD) for top-down proteomics. As a postdoctoral researcher at the Pacific Northwest National Laboratory (PNNL), Jared became an expert in Fourier transform mass spectrometry (FTMS) while leading development of a 21 tesla Fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS). In 2016, he was promoted to a senior research scientist at PNNL and led efforts to develop and apply novel FTMS instrumentation and methods to top-down proteomics and native mass spectrometry. Through industrial collaborators, Jared was introduced to and began collaborating with the team at e-MSion in 2017. This fruitful collaboration led to advances in de novo antibody structure characterization and novel approaches to the characterization of native protein complexes. Jared joined e-MSion as Chief Scientific Officer in February of 2020.
Nathan Lopez graduated in 1999 from Oregon State University with a B.S. degree in Microbiology and a minor in Chemistry. After graduation, he worked as a technician and eventually lab manager at OSU. In this time he honed a diverse set of valuable skills ranging from molecular genetics to project management to materials science. As Manufacturing Lead at e-MSion, Nathan’s do-it-all approach has been invaluable for solving technical problems related to design, manufacturing, management, and everything in between.
Adrian Guthals received his BS in Bioinformatics at UCSD, where he stayed for graduate school earning a MS and Ph.D in Computer Science. In his research Adrian has developed methods for monoclonal and polyclonal antibody sequencing, as well as more general approaches for MS/MS peptide identification. He has also worked on computational platforms for small molecule identification and subsequent drug discovery.
Joseph Meeuwsen joined e-MSion in 2018 while working toward his PhD in Molecular & Cellular Biology at Oregon State University. He used mass spectrometry in his PhD research to study metal-binding proteins in the context of the neurodegenerative disease ALS. During his graduate training, he also earned a Graduate Certificate in College and Undergraduate Teaching and participated in the Lens of the Market program for translating research into commercial ventures. These endeavors positioned him at the interface of mass spectrometry, scientific communication, and technology commercialization. As a Product Specialist at e-MSion, he is involved in research & development, product applications, marketing, documentation and training.
Yury Vasilev Ph.D is a physicist whose expertise spans mass spectrometry and photoelectron spectroscopy. He has many years of experience in the design and construction of electron guns with small energy spreads (also known as electron monochromators). He applies quantum chemical calculations and statistical approaches to understand precisely how electron energies affect ion fragmentation pathways.
Mike Hare received a Ph.D. in physical organic chemistry from The University of Minnesota in 1998 for studies of the gas phase reactions of organic anions using a high-pressure flow-type reactor, FTMS mass spectrometry, and computation. He has worked in the mass spectrometry service lab at both Minnesota and Oregon State, with experience ranging from small molecule mass spectrometry to proteomics. At e‑msion since April 2019, Mike is developing applications for the ExD cell. He has used its unique capabilities for example to map disulfide bonds, confirm the sequence of monoclonal antibodies, and demonstrate the utility of electron capture in analysis of post-translational modifications.
Blake Hakkila graduated from Oregon State University in 2018, earning his Honors Bachelor of Science degree in Biochemistry and Biophysics. He wrote his undergraduate thesis on the purification and characterization of temperature-sensitive mutants of otoferlin, a calcium-sensing protein necessary for hearing. He now works as a Development Engineer at e-MSion, Inc., where he currently focuses on product research and development, manufacturing engineering, and software development.
Brett Meador graduated magna cum laude from Oregon State University (OSU) in 2020, with a H.B.S. in Mechanical Engineering and as an Honors Scholar. He wrote his Honors Thesis on the design of liquid feeding systems for honey bees in the lab, and designed cages for bee research for the OSU Department of Horticulture. While attending Oregon State, he worked for the OSU Product Development Lab. He has also worked in agriculture, manufacturing, and designing cemetery plot markers. He started working for e-MSion as an intern while he was a senior at OSU and is excited to join a fast-growing firm in engineering pursuits.
Cordell has a two-year certificate in Manufacturing and an Associate of Science degree from L.B.C.C. He is responsible for the assembly of all e-MSion ExD cells & wire harnesses. Cordell has been with e-MSion since Aug of 2019.
Kim Lopez graduated from Oregon State University with a bachelor’s degree in Public Health. She works as a procurement agent securing essential supplies for the safety and productivity of our team. Kim joined the team at e-MSion in May 2018.